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Biomedical Sciences Institute at Trinity College Dublin features Five Nobel Laureates as Key Note Speakers

The symposium, entitled ‘Medical Research at the Cutting Edge’ jointly organised with the Weizmann Institute of Science.

Five Nobel Laureates delivered keynote addresses at a medical research symposium showcasing advances in the fight against inflammatory diseases and cancer at the Trinity Biomedical Sciences Institute (TBSI).

The Nobel Laureates included geneticist James Watson, biologists Aaron Ciechanover and Jules Hoffmann, immunologist Bruce Beutler, and chemist Ada Yonath.

James Watson won the Nobel Prize (Physiology or Medicine) in 1962 for his part in discovering the double-helix structure of DNA.

The five Nobel Laureates spoke about their research in the context of the improvement of human health and the development of new medical advances.

Also speaking at the symposium was Marc Feldmann, the 2003 winner of the Albert Lasker Award for Clinical Medical Research and 2014 winner of the Gairdner Prize, for the discovery of anti-TNF therapy for rheumatoid arthritis.

The symposium  started on the evening of Sunday, July 27th, with an opening address given by the president of the Royal Irish Academy, Professor Mary Daly. There was an official signing of a Memorandum of Understanding about the planned cooperation of Trinity College Dublin and the Weizmann Institute of Science.

The symposium was the joint initiative of Professor of Biochemistry at Trinity and Academic Director of TBSI, Luke O’Neill, and Professor David Wallach of the Weizmann Institute of The symposium concluded with a special session on the commercialisation of breakthroughs in biomedicine research. Speakers included Mark Ferguson of Science Foundation Ireland and Director of Trinity Research and Innovation, Diarmuid O’Brien, who is responsible for commercialisation of intellectual properties at TBSI.  Mudi Sheves, the Weizmann Institute’s vice president for technology transfer, also spoke about the Institute’s highly successful technology transfer mechanism.

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Key Words:

Technology transfer, biomedical research, commercialisation of intellectual property, Trinity Biomedical Sciences Institute, health, medical research.

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Amazing piece on how big data is being used in hospitals, the impact for patients and Healthcare Entrepreneurs

The BBC’s Horizon, a long-running British documentary television series that covers science and philosophy, recently featured an amazing piece on how big data is being used in hospitals called Achieving Small Miracles from Big Data.

A tiny baby, born 15 weeks early, fights for every breath in her hostile new environment. In the neonatal intensive care unit (NICU), she is tethered to nearby medical devices that continuously measure her heart rate, respiration and other vitals – generating minute-by-minute readings of her fragile condition.

The doctors who care for these babies are faced with extremely complex decisions about how to treat them, how to best monitor their condition and stave off infection. All too often, this potentially life-saving data is more than clinicians can absorb and analyze.

Enter Project Artemis, a collaborative initiative involving Toronto’s Hospital for Sick Children, the University Of Ontario Institute Of Technology (UOIT) in Oshawa, Ont., and IBM Canada.

The goal of the project is to capture and analyze vast amounts of physiological data from premature babies and then present that information to physicians and nurses.

The project is led by Dr. Carolyn McGregor, a Canada  Research Chair in Health Informatics at UOIT who is using  IT to help clinicians detect life threatening infections days  sooner than is possible today

Further Reading

Carolyn McGregor Canada Research Chair in Health Informatics

Harness your data resources in healthcare

The ‘big data’ revolution in healthcare – McKinsey & Company


Big data, IBM, Healthcare Entrepreneurs ehealth, healthIT, innovation, electronic health records

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Renowned US Angel Bill Payne talks about trends in pre-money valuations and sourcing funding for seed investment and start-ups.

Bill and his wife visited Ireland, Russia, Estonia and Finland, from mid-March to mid-April (2012), sharing experiences in angel investing through lectures, discussions and workshops.

Bill Payne

Bill Payne

On Thursday 19th, Bill spoke to entrepreneur groups at both the National Digital Research Center and the DIT Hothouse on subjects of fundable companies, trends in funding, business plans

I was lucky enough to attend Bill’s excellent lunch time talk and had an opportunity to chat with him afterwards.

In Ireland, he spent 19 hours in front of audiences, delivering eight lectures and workshops to 162 entrepreneurs and 190 angel investors.

Bill covered a number of topics including that business plans have many forms. When entrepreneurs come to the attention of potential investors, they may be invited to make verbal presentations to a select group of investors. This is commonly accompanied by a PowerPoint presentation.

Here is the content that Bill emphasised should be included in your investor pitch

A Cover Slide: Company name, business one-liner, your contact information (doesn’t count as one of the 10).

1. Market – What solution does the product/service provide to customers that they absolutely cannot live without – a “must have?” Investors do not fund products that are “nice to have.” What is the size of the addressable market? (Assuming all customers purchased the product, what would be the annual revenues?)

2. Solution – Describe the product(s), the features and benefits of the product, the intellectual property that precludes the competition from immediately copying the product and the customer feedback that validates the market demand. What is unique about your solution?

3. Competitive Position – Who are the competitors, what are their strengths and weaknesses, and what are your advantages over the competition.

4. Marketing /Sales /Support – How will you make customers aware of the product? What is your value proposition to customers? How will you establish a recognizable brand? How will you sell the product (describe sales channels)? How will you provide product and technical support to your customers? How long is your sales cycle?

5. Business Strategy – Most of us know how to find the first customer for a product. But, it is more difficult to describe how to grow the business. What partnerships, team members, facilities and capital will be required to achieve the five-year plan?

6. Financial Projections – The usual spreadsheets: Income statements, balance sheets and cash flow projections for the first five years of operations.

7. Funding Sought – How much money do you need to achieve early milestones? How much additional funding will be necessary to achieve positive cash flow? Will even more money be required to maintain optimum growth? From what sources to you expect to raise these funds?

8. Management – What is the relevant background and experience of the existing team? Describe the characteristics of additional team members that will be required to achieve positive cash flow. Describe your advisors and board of directors.

9. Milestones – Investors want to know how this round of funding will increase the value of the company. What accomplishments can the company achieve with the currently sought capital and how will that increase the valuation of the company?

10. Exit Strategy – IPOs are no longer a rational expectation for startup companies. Yet, investors are keenly interested in achieving a positive return on investment from startup ventures.

Which large public companies might be interested in buying this company and why? What does the company need to achieve to attract potential acquirers?

Bill Payne is an active angel investor, board member, and advisor to entrepreneurs. He assisted in founding four angel groups: the Frontier Angel Fund (2005),   Tech Coast Angels (San Diego – 2000), Vegas Valley Angels (2003) and Aztec Venture Network (1999).

Bill Payne

Bill Payne

For three decades, Bill Payne has successfully founded or invested in over 50 start-up companies.  He served as an Entrepreneur-in-Residence to the Kauffman Foundation for twelve years.

While there, he directed the development of the Power of Angel Investing education series for entrepreneurs and angel investors.  He has served as lead instructor for over 100 seminars in seven countries.

In 2009, Bill was named the Hans Severiens Award winner as the “outstanding angel investor in America.”

Related links

  • If you are interested in learning more about Bill Paynes system for ensuring you are investment ready check out his website on
  • Click here for a download of his slides: pdf the slides and have as a down load. Put a front end baily on it though CTA slide at the end to get their e mail

Further Reading

Key words

Angel investing entrepreneur, business plans, seed finance, start up, Bill Payne, valuation, sourcing capital

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How IOS 8 will be a great opportunity for Healthcare Entrepreneurs

As a biomedical entrepreneur (doctrepenuer or even appreneur) whenever Apple releases updates and features, there’s a tremendous amount of opportunity. …

It’s these updates and software changes that keeps the app market growing. People often assume the health app and m-health market is crowded, but they don’t realize that with each new update, it opens the door for hundreds of new health care related innovations and apps opportunities.

iphone for ehealth-mhealth

Biomedical Consulting eHealth

This year Apple has released a couple updates that will be particularly relevant for health.

There are crucial feature changes with Health app and HealthKit that allow more cross-app functionalities which will opens the door for tons of new health app ideas.

Fitness & Health is huge for mobile health more than ever. The new “Health” app can pull in data from other third-party apps to keep all your health-related information in one.

Developers will use the service called HealthKit to integrate their apps with the Health app. Being able to integrate your app within Apple’s framework increases accessibility and downloads.

Apple is also allowing apps as a “public beta download” through TestFlight.

This means users will be able to try out early versions of health apps before the launch, which provides feedback by patients and consumers prior to release.

What health and wellness related apps can you make with these new features?

This should be a breakthrough year for health apps.

Tweet me to share your thoughts! @DrJMckeon

Further Reading

Digital Health funding environment gets friendlier in Europe

4 Lessons for Healthcare Entrepreneurs

Why Are Telemedicine Solutions So Expensive?


M-health, health apps, ehealth, healthIT, innovation, electronic health records. HealthKit; TestFlight, IOS 8

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International Council for Small Business – World Conference on Entrepreneurship 2014

The 59th Annual International Council for Small Business World

Conference took place in Dublin, Ireland from11-14 June 2014 at Double Tree by Hilton Dublin

Last week as part of ICSB 2014 World Entrepreneurship Conference I attended a dedicated Entrepreneurs Day on Wednesday June 11th organised by the Dublin Institute of Technology. This day was titled Standing out from the crowd; funding innovation and leadership

This event was targeted at those entrepreneurs who wish to learn first-hand how successful entrepreneurs have grown their businesses from start-ups to commercially thriving operations. The day focused on creativity, funding, leadership innovation  as well as  social media as it is applicable business.

It was a very comprehensive series of talks which included addresses from Raomal Perera on how to raise money through successful crowd funding campaigns and Nigel Newman from the DeBono Foundation encouraging lateral thinking and reimagining success by helping to release and realise creativity within organisations.

Serial entrepreneur Noelle O’Connor and Dragon’s Den star Gavin Duffy  also gave their insights into building successful businesses in Ireland

The final address of the day was given by Michael Houlihan and Bonnie Harvey who are serial entrepreneurs, industry reformers, successful brand builders, and co-founders of hugely successful Barefoot Cellars.

It was a great forum for entrepreneurs to talk practically with fellow entrepreneurs and I certainly left with a better understanding of good leadership skills, new problem solving techniques and a fresh approach to social media for success.

Thanks to the DIT for organising and I along with my fellow entrepreneurs certainly left with several new ideas that will be readily implemented.

Key words

Entrepreneurship, funding, innovation, leadership, Serial entrepreneur, crowd funding, brand, success, social media,

Related links

Further reading

Twitter handles to look at


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Dr John McKeon joins prominent speakers and recognized experts, as key note at Asthma Society of Canada’s 40th Anniversary Summit, For Life and Breath.

Prominent speakers and recognized experts, including the federal Minister of the Environment, the Honourable Leona Aglukkaq, met in Toronto earlier this month for the Asthma Society of Canada’s 40th Anniversary Summit, For Life and Breath.

The event looked at the link between health and the environment, particularly respiratory health and air quality.

Click here to read the final event agenda.

The summit audience heard from a variety of speakers on topics ranging from air pollution and its affect on asthma and allergies, indoor air quality, new treatments and technologies for people with asthma and allergies, regulation of pollen, and much more!

Additionally, the Asthma Society celebrated the contributions of three key individuals, whose work has dramatically helped improve the lives of Canadians with asthma and respiratory allergies.  These individuals received inaugural For Life and Breath Innovation Awards in the fields of:

  • Public and Population Health Research – Dr. Michael Brauer
  • Industrial Design – Sir James Dyson
  • Public Policy – Elizabeth Witmer

Additionally, Dr. Brauer was awarded the first-ever Bastable-Potts Asthma Research Prize. Read More…

Most speaker presentations will be made available in the near future.

We hope to see you at 2nd annual event in 2015!

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The Real Wolf Of Wall Street- Jordan Belfort Entrepreneurship and Innovation Seminar in Dublin

Jordan Belfort

Jordan Belfort

On May 27th I attended Jordan Belfort giving his seminar The Truth Behind The Success Of The Real Life Wolf Of Wall Street, in Dublin.

Jordon inspired the Hollywood blockbuster The Wolf of Wall Street delivered a great talk courtesy of including his formula for success and creating wealth.

Belfort, who had made more than $50 million by his mid-twenties and had raised over $1.5 billion in venture capital, started up multiple companies also revealed the eight skills he feels you must know for business, sales and entrepreneurial success.

The businessman’s autobiographical book, The Wolf of Wall Street became a New York Times best seller sold millions, sparking interest from Hollywood. The movie, directed by Martin Scorsese, was based on the motivational speaker’s book. It grossed over $375 million worldwide and landed lead Leonardo DiCaprio an Oscar nomination.

Jordon was speaking in Dublin as he is convinced now is the “greatest time” in Ireland for start-ups to make their fortune.

“The greatest opportunities are after the cataclysm – but very few people will really take advantage of them,” he said. “Those who do it are the vulture guys – who will swoop in when things are at the bottom. “Jobs are created and wealth is created that way, so I would really try to encourage an entrepreneurial mindset,” he said.

Now, a decade after his conviction and after serving 22 months of a four-year prison sentence and being ordered to repay $110.4 million to a victims’ compensation fund, Belfort has turned his notoriety into a business as an entrepreneur

Through his company, Jordan Belfort Global, he is an author and a motivational speaker based out of Manhattan Beach, California.

Interestingly his Ex-partner Porush, has started a successful medical supply company in Florida after doing his prison sentence.

Here are some lessons from Belfort’s entrepreneurial path from his recent blog post.

  1. Listen to wise men: Belfort came up with the idea to write a book about his life from his cellmate who happened to be Tommy Chong, of Cheech and Chong fame. Chong was in prison for some entrepreneurial activity of the illegal variety: serving time for selling bongs over the internet. Chong found Belfort’s stories hilarious and urged him to write them down. Belfort read and studied Tom Wolfe classic The Bonfire of the Vanities while in jail to figure out how to write his own story.
  2. Know how to verbalize your story: Dan Alonso, a former federal prosecutor who handled Belfort’s case, was so impressed with Belfort’s speaking chops that after he got out of jail, he invited him to the Manhattan district attorney’s office, where Alonso works now, to give a speech to prosecutors in that office. He also goes to dinner regularly with the FBI agent who made the case against him, who told New York magazine that Belfort “was a reprehensible” guy from a moral perspective, but today, Belfort now 51, can still entertain with his stories.
  3. Think rich: As a motivational speaker, Belfort focuses on teaching people about wealth creation. “I believe in total immersion, if you want to be rich, you have to program your mind to be rich,” he said. “You have to unlearn all the thoughts that were making you poor and replace them with new thoughts—rich thoughts.”

Further reading

Jordan Ross Belfort. (2014). The website. Retrieved 12:52, May 30, 2014, from

Key words

Entrepreneurship, Sales, Innovation, persuasion, communication, venture capital, wealth, success, business skills, small business owners, start ups.

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Innovation Master Class by Darrell Mann one of the world’s most prolific inventors

Why do 98% of Innovation projects end in failure? Today in Dublin he gave a master class on his approach called Systematic Innovation.

28th Feb 2014 

Dr John McKeon with Darrell Mann

Dr John McKeon with Darrell Mann

Darrell was at IMI today speaking at the Industry Research & Development Group (IRDG) conference on Systematic Innovation.

‘Systematic Innovation’ is all about helping organisations to construct a repeatable formula for success.

Based on an analysis of over 3.8 million innovation attempts across every sector of human activity, the likelihood of successfully turning a novel idea into sustainable shareholder value is currently slightly worse than the odds of winning at roulette. Close to 98% of all innovation attempts end in failure.

Those attempts fail because organisations: – Ask the wrong questions – Deliver the wrong solutions – Inadequately protect their IP – Mis-handle the communication with customers & stakeholders – Take on projects inconsistent with the capabilities of the organisation – Give up too soon.

Darrell examined each of the above failure reasons to provide us with proven, deployable strategies appropriate to the context of our own enterprises.

In the workshop, Darrell addressed each of these modes of failure in their R&D context, and extracts from the 3.8 million datapoints the strategies and principles uncovered by the 2% of innovation attempts that end up being successful.

Successful innovations also come through understanding your customers (and those that aren’t yet your customers) better than they understand themselves.

True understanding of customers means anticipating their current and future needs. It also means understanding intangible and unspoken desires as well as their known tangible ones.

The programme is the outcome of over 2000 person years of research into the DNA of creative success. It is the only philosophy, method and toolkit capable of tackling and generating breakthrough solutions in today’s challenging and increasingly complex business environment.

Key Topics Darrell covered were

1) Big Picture – Why so much R&D results in so little innovation

2) Understanding Customers Better Than They Understand Themselves

3) Generating Breakthrough Solutions – Finding & Eliminating Trade-Offs

4) Bulletproofing IP – Predictable Evolution Directions

5) Innovation Capability

6) Putting It All Together – Top 5 Things To Do Differently Tomorrow

About Darrell Mann

Featured in Who’s Who in the World, Darrell Mann is recognised as one of the world’s most prolific inventors and has generated over a dozen patents and patent applications. He has spent much of his working life trying to understand why 98% of Innovation projects end in failure and has come up with an approach called Systematic Innovation.

He now implements this approach with clients including Intel, Hewlett Packard, Procter & Gamble, General Motors, Nestle, & Mahindra, MindTree, Samsumg, Telekom Malaysia, Hong Kong government & many more. His early career was spent in various R&D roles at Rolls-Royce before he became chief engineer responsible for the company’s long-term military engine strategy.

About the IRDG

 The Industry Research & Development Group (IRDG) is a non-profit, business-led Innovation Network of member companies, working together to drive excellence in Innovation within Ireland’s industry to create growth, jobs and prosperity.  Membership of the IRDG is extensive, including indigenous and multinational organisations, of all sizes, across all sectors of industry.  The common theme that brings all members together is their interest in progressing their business through Innovation & R&D. We took the opportunity to catch up with Darrell between international flights to ask him about extending his advice to the broader business community… in just six words of course

About the IMI

IMI is a membership organisation that reflects a spectrum of Irish industry, from the smallest micro-organisations to the world’s largest multinationals. For sixty years IMI has pioneered the development of executive education in Ireland. Thousands of senior executives attend developmental programmes at IMI annually, ranging from NFQ level 9 Masters and Diploma qualifications to one and two day master classes. IMI also acts as a “business partner” for organisations that are looking to align comprehensive learning and development strategies to support the execution of business growth strategies.

Key words

Innovation, Marketing, Technical, R&D, Leadership, IP, intellectual property, patent, Systematic Innovation

Further reading

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Interview with Dr Patrick Prendergast, Provost of Trinity College Dublin on Innovation

by Lynne Nolan

Dr Patrick Prendergast, Provost of Trinity College Dublin

Has the Government made progress in creating a smart economy, and how has Trinity College Dublin played its role?

It is not solely Government’s responsibility to create a smart economy. There are many players involved, including Government, the private sector, industry and the universities.  Government has an enabling role and has taken positive steps, not least continuing its commitment to fund research through Science Foundation Ireland and new ventures through Enterprise Ireland.  Universities like Trinity play a critical role by providing education and skilled graduates as well as providing knowledge and innovation that translates into spin-outs and technology transfers. Specifically in the high-tech area, computer science at Trinity is involved in leading research such as CTVR, the national telecommunications research centre, the CNGL Centre for Global Intelligent Content, and Learnovate. It has also increased its numbers of PhD students and has strong ties with industry such as Google, Intel among many others.  Additionally, Trinity’s Innovation Academy educates PhD students to recognise the innovation potential of their research and to exploit their ideas in a competitive world. We are also shortly going to launch Trinity’s Innovation and Entrepreneurship Strategy that will further embed a culture of innovation entrepreneurship throughout the University reflecting our commitment to playing this pivotal role for Dublin and for Ireland.

For Ireland, innovation can become the engine of sustainable prosperity. This can only happen if Government, universities and industry work together in partnership, supported by the right mix of policy and investment. Dublin, with Trinity located in the city centre, is developing a global reputation as an innovation hub. The high-quality, high-productivity jobs in the innovation sector, whether in multinationals or indigenous companies, have a strong multiplier effect because they generate knock-on jobs in the non-traded, services economy. So, innovation can be the rising tide that lifts all boats. That’s where the future is for Ireland – creating vibrant, jobs-rich economic clusters. Trinity can be at the heart of that endeavour.

What are the most sought-after IT-related courses at TCD?

There is huge take up of IT courses at Trinity. Students recognise the career opportunities   within the industry and we continue to provide capacity building programmes to meet that demand, from undergraduate level to postgraduate to graduate programmes and evening courses.

There are six undergraduate degrees, including computer science, engineering, and management science and information systems studies.  At postgraduate level there are a range of taught masters in computer science as well as health informatics, technology and learning and interactive digital media. Just to note it is not all about technology and the creative arts are also strong in this area with courses such as music and media technologies.  We know that employers attend the annual MSc Showcase and jobs fair with job offers being made on the spot.

What are the latest trends in relation to interest in IT-related courses?

The latest trends include mobile apps, web apps, intelligent content, big data, data analytics, software engineering techniques (SCRUM) for large-scale programming development and formal verification of parallel systems. The demand is high and the numbers of graduates have accelerated in the last few years.

Have there been advances made in addressing the skills gap?

A critical advance in addressing the skills gap has been the introduction of a masters level qualification with industrial internship. This has meant an overall upgrading of the quality of education provided. Industry indicated that companies required graduates trained to masters level.  Our School of Computer Science and Statistics addressed this issue by adding a fifth year to their existing accredited computer science and computer engineering degree programmes.  The additional fifth year confers them with a Master in Computer Science in addition to great experience that they gain from their six month industry internship.  This has proved to be very popular with industry from small indigenous start-ups to large multinationals. We also got Springboard funding for a small number of students aimed at reskilling existing graduates.

How has the education system’s focus on upping IT-related skills contributed to economic growth?

Ireland’s economic growth is very dependent on the success of the IT related sector. The Irish education system has contributed greatly in providing training, skilled graduates and research outputs.  Here at Trinity our IT  graduates have gone on to establish many successful companies, Havoc, DemonWare, to name but a few. The experience gained in these companies has led to a strong infrastructure for the next generation of entrepreneurs.  We are also helping to identify, encourage and educate young people to follow computer science and engineering related careers.  One example is the recent Google- supported initiative involving our computer scientists, Bridge21, and Trinity Access Programmes, to educate current and future teachers in the more problem solving teaching methodologies that will further increase interest in computer science.

Are we responding appropriately to the requirements of multinationals?

Multinationals have been able to source skilled graduates for employment with the appropriate training. I am getting this positive feedback from leaders of industry that I meet. Here at Trinity College we are actively engaged in dialogue with leading IT multinationals, directly and through industry bodies, providing the best educational outcomes for our graduates and the sector. But, I think it is also worth noting that it is not just the role of universities to train our graduates for one single multinational. We provide them with an education for a career for life. They are skilled for employment and will adapt to any single multinational on entering employment there.

We must remember that the IT skills gap is not just a function of the multinational sector. Our indigenous IT companies are a key part of Ireland’s innovation platform. The indigenous software technology sector has over 600 companies, employing more than 10,000 people, and contributing €1.4 billion to the economy every year. Trinity has a strong role to play in equipping graduates with the skills they need to get jobs in the broad-based IT sector. And we can also help to foster a new generation of job creators through our new innovation and entrepreneurship strategy and the emphasis we place on bridging academic research and industry through open innovation strategies.

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Researcher Night at the Innovation Academy

On the 27th September, Trinity College will open its’ doors to the general public to promote research across college. The Innovation Academy in 3 Foster Place will be transformed by PhD researchers demonstrating their research in fun, interactive ways.  The aim is to give the public the opportunity to meet researchers and experience activities, hands-on demonstrations, digital displays, games or just plain old-fashioned talking. We are inviting all of our industry contacts, contributors, students past and present, the wider college community and the general public.

Discover Research Dublin @ The Innovation Academy
The full Innovation Academy programme can be viewed here Please feel free to share with your own networks.

The evening kicks off at 18.00 with what promises to be an engaging industry/academia panel trashing out the real value of doctoral education titled ‘“Research Assembly Line – the mission of PhD education in Ireland?”

Researcher-Night-at-the-Innovation-Academy-panel7pm – 10pm: Life’s a Pitch dives into the life of a PhD student and how they spend their day (and night!). Everything from fancy laser shows, Herod the Great to ancient Crustacea will be on show. It is a perfect opportunity to find all you ever wanted to know about PhD life. The evening will be spotted with fun Lego Challenges and Treasure Trails. Fun for everyone guaranteed!

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